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1.
Cancer Research, Statistics, and Treatment ; 5(1):85-87, 2022.
Article in English | EMBASE | ID: covidwho-20241186
2.
Cancer Research, Statistics, and Treatment ; 4(1):158, 2021.
Article in English | EMBASE | ID: covidwho-20241003
3.
Cancer Research, Statistics, and Treatment ; 5(2):212-219, 2022.
Article in English | EMBASE | ID: covidwho-20240615

ABSTRACT

Background: During the coronavirus disease 2019 (COVID-19) pandemic, established best practices in cancer care were modified to diminish the risk of COVID-19 infection among patients and health-care workers. Objective(s): We aimed to study the modifications in cancer-directed therapy during the first wave of the COVID-19 pandemic. Material(s) and Method(s): A cross-sectional study of patients with cancers of the head and neck, thoracic, urologic, and central nervous systems who visited the medical oncology department of the Tata Memorial Hospital, Mumbai, India, between April 22, 2020 and June 01, 2020, was conducted. Data were prospectively collected in an online pro forma and supplemented from the electronic medical records. Result(s): Of a total of 514 patients, 363 (71%) were men. The most common malignancy was lung cancer in 234 patients (46%). Cancer-directed therapy was modified in 83 patients (16%). Deviations consisted of modification of the chemotherapy regimen (48%), temporary discontinuation of chemotherapy in 37%, and interim chemotherapy to delay surgery in 5%. Changes in the chemotherapy regimen included a shift to a less intensive regimen in 45%, changing from intravenous to oral in 40%, and less frequent dosing of immunotherapy in 7%. Considering missed appointments as a deviation from planned cancer therapy, 68% of patients had a deviation in the standard planned cancer care. Conclusion(s): Almost two-thirds of the patients could not reach the hospital during the COVID-19 pandemic lockdown in India. Of those who could reach the hospital, one of out every six patients with cancer had a change in their cancer-directed treatment, half of which consisted of a modification in the standard chemotherapy regimens. The effects of these therapy deviations are likely to be long-lasting. (Clinical Trials Registry-India, CTRI/2020/07/026533).Copyright © 2023 Neurology India, Neurological Society of India Published by Wolters Kluwer - Medknow.

4.
Cancer Research, Statistics, and Treatment ; 4(2):211-218, 2021.
Article in English | EMBASE | ID: covidwho-20240614

ABSTRACT

Background: Patients with cancer are at a higher risk of severe forms of coronavirus disease 2019 (COVID-19) and mortality. Therefore, widespread COVID-19 vaccination is required to attain herd immunity. Objective(s): We aimed to evaluate the uptake of the COVID-19 vaccine in Indian patients with cancer and to collect information regarding vaccine hesitancy and factors that contributed to vaccine hesitancy. Material(s) and Method(s): This was a questionnaire-based survey conducted between May 7, 2021 and June 10, 2021 in patients aged 45 years and over, with solid tumors. The primary end points of the study were the proportion of Indian patients with cancer aged 45 years and older who had not received the COVID-19 vaccine, and the reasons why these patients had not received the COVID-19 vaccine. Our secondary end points were the proportion of patients with a history of COVID-19 infection, and the proportion of the patients who had vaccine hesitancy. Additionally, we attempted to assess the factors that could impact vaccine hesitancy. Result(s): A total of 435 patients were included in the study. Of these, 348 (80%) patients had not received even a single dose of the COVID-19 vaccine;66 (15.2%) patients had received the first dose, and 21 (4.8%) had received both the doses. Approximately half (47.1%) of the patients reported that they took the COVID-19 vaccine based on the advice from a doctor. The reasons for not taking the COVID-19 vaccine could be considered as vaccine hesitancy in 259 (77%) patients. The two most common reasons were fear in 124 (38%) patients (fear of side-effects and of the impact of the vaccine on the cancer/therapy) and lack of information in 87 (26.7%) patients. On the multivariate analysis, the two factors found to be significantly associated with vaccine hesitancy were a lower educational level (OR, 1.78;95% CI, 1-3.17;P = 0.048) and a lack of prior advice regarding the COVID-19 vaccine (OR, 2.80;95% CI, 1.73-4.53;P < 0.001). Conclusion(s): Vaccine hesitancy is present in over half of our patients, and the most common reasons are a fear of the vaccine impacting the cancer therapy, fear of side-effects, and lack of information. Widespread vaccination can only be attained if systematic programs for education and dissemination of information regarding the safety and efficacy of the COVID-19 vaccine are given as much importance as fortification of the vaccination supply and distribution system.Copyright © 2021 Cancer Research, Statistics, and Treatment Published by Wolters Kluwer - Medknow.

5.
Chinese Journal of School Health ; 44(4):590-593, 2023.
Article in Chinese | Scopus | ID: covidwho-20238936

ABSTRACT

Objective To analyze the disinfection quality and influencing factors of nurseries in Nanjing during 2019-2021 so as to provide a scientific basis for optimizing preventive disinfection strategies and measures in nurseries. Methods Environmental samples from 389 nurseries in Nanjing from January 2019 to December 2021 were tested and the change of disinfection quality qualification rate was compared. Results The overall disinfection qualification rate of nurseries of year 2019-2021 were 96.32% 95.85% and 94.60% respectively showing a downward trend χ2trend = 8.67 P<0.05 . Specifically disinfection qualification rate of object surfaces staff hands and tableware showed a downward trend while the disinfection qualification rate of dynamic air showed an upward trend and the differences were statistically significant χ2trend = 23.17 12.32 5.37 21.48 P<0.05 . The total qualification rate of disinfection in Jiangning and Liuhe districts increased during 2019-2021 χ2trend = 21.46 24.05 P<0.05 . Conclusion Disinfection quality of nurseries in Nanjing has declined by year during 2019-2021 especially the object surfaces and staff hands. It is urgent to optimize and refine the strategies and measures for preventive disinfection in nurseries strengthen the training of personnel on disinfection knowledge and ensure the quality of disinfection in nurseries. © 2023 Chinese Journal of General Surgery. All rights reserved.

6.
Journal of Pharmaceutical Negative Results ; 14(3):2587-2599, 2023.
Article in English | Academic Search Complete | ID: covidwho-2314328

ABSTRACT

This study has examined the principles of care of the medical staff for the elderly with fracture problems and corona virus in the special care unit. While the Chinese health authorities had previously reported the average age of the disease to be 75 years. Elderly people, especially people with lung problems, have a mortality rate of about 15%. The coronavirus acts like a seasonal flu. According to the US Centers for Disease Control and Prevention (CDC), between 70 and 85 percent of all flu-related deaths and 50 to 70 percent of flu-related hospitalizations are among people over the age of 65. The most at-risk group is the elderly who live in day care centers. Among recovered patients with coronavirus in China, there is evidence that some of these patients have longterm lung damage. The researchers announced that among the 70 recovered patients, lung damage was observed in 66 of them in the CT scan. These injuries are caused by a build-up of hardened tissue that blocks blood vessels in tiny air sacs called alveoli, said Yuhei Wang, a radiologist at Huazhong University of Science and Technology in Wuhan, China. Alveoli absorb oxygen to form tissue debris around them. Tissue lesions can be a chronic symptom of lung diseases, including SARS and MERS, similar injuries were observed in recovered patients. [ FROM AUTHOR] Copyright of Journal of Pharmaceutical Negative Results is the property of ResearchTrentz and its content may not be copied or emailed to multiple sites or posted to a listserv without the copyright holder's express written permission. However, users may print, download, or email articles for individual use. This may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full . (Copyright applies to all s.)

7.
Entrepreneurship Theory and Practice ; 47(3):788-830, 2023.
Article in English | ProQuest Central | ID: covidwho-2292837

ABSTRACT

We investigate the effect of the COVID-19 pandemic on self-employed people's mental health. Using representative longitudinal survey data from Germany, we reveal differential effects by gender: whereas self-employed women experienced a substantial deterioration in their mental health, self-employed men displayed no significant changes up to early 2021. Financial losses are important in explaining these differences. In addition, we find larger mental health responses among self-employed women who were directly affected by government-imposed restrictions and bore an increased childcare burden due to school and daycare closures. We also find that self-employed individuals who are more resilient coped better with the crisis.

8.
Acta Stomatologica Croatica ; 56(4):417, 2022.
Article in English | EMBASE | ID: covidwho-2292548

ABSTRACT

Introduction: Aim of the study was to analyse the structure of patients referred for dental treatment in general anaesthesia (GA) and to analyse the triage outcomes. Material(s) and Method(s): Retrospective chart analysis of patients referred between January 1st 2018 and July 7th 2022 was performed. Following data were registered: age, sex, diagnosis/ reason for referral for GA, indication for dental treatment in GA, trisage outcome and waiting time for the GA procedure. Result(s): Charts of 193 referred in the aforementioned period were analysed. Most common reason for the referral was autism (65/33.7%), cerebral paralysis (29/15%) and mental retardation (27/14%). Indication for dental treatment in GA was found in 156(80.8%) patients while in 37(19.2%) patients no indication for dental treatment in GA was found. Out of the 156 patients who were indicated for dental treatment in GA, 98(62.8%) patients were managed through day-care surgery and 8(5.2%) patients were admitted to hospital. Twenty patients (12.8%) were still waiting for their GA appointment in the time of analysis, 29(18.6%) were lost to follow up and in one (0.6%) patient the anaesthesiologist recommended ambulatory treatment due to increased risk. Out of the 37 patients in whom no indication for the treatment in GA was found, 13(35.2%) had no caries, 16/ (43.2%) were referred to paediatric dentist and 8(21.6%) were managed on the initial exam. Median time of waiting for the procedure was 120(10-365) days. Before the COVID- 19 pandemics median waiting time was 90(15-300) days, and after the COVID-19 pandemics median waiting time was 135(10-365) days. Conclusion(s): In the majority of the patients referred for dental treatment in GA, indication for the procedure was established. Majority of the referred patients can be managed through a day-care surgery. COVID-19 pandemics is probably one of the reasons for the increased GA procedure waiting time.

9.
Pharmaceutical Journal ; 306(7947), 2021.
Article in English | EMBASE | ID: covidwho-2276807
10.
Occupational Health and Emergency Rescue / Zhiye Weisheng yu Yingji Jiuyuan ; 40(5):548-553, 2022.
Article in Chinese | GIM | ID: covidwho-2268844

ABSTRACT

Objective: To understand the occupation burnout of community medical staff during epidemic and explore the influencing factors, so as to improve the mental health level of medical staff. Methods: Totally 843 community medical staff in the central urban area were studied. They were surveyed by a face-to-face with the questionnaire of JCQ, ERI and MBI. Results: Totally 835 valid questionnaires were recovered with an effective response rate of 99.1%. JCQ mode showed that the detection rate of occupational stress was 42.5%. The ERI mode showed the detection rate of occupational stress was 34.0%. The incidence of job burnout was 50.8%, of which the incidence of mild and moderate job burnout was 42.2% and the incidence of severe job burnout was 8.6%. The logistic regression analysis showed that the risk of job burnout of community medical staff was increased (P < 0.05), OR = 1.546 (aged 40 to < 50 years vs. aged < 30 years), OR = 1.506 to 1.707 (working time more than 10 years vs. less than 10 years), OR = 2.085 (working in public health departments vs. in clinical departments), OR = 2.408 (working more than 50 hours per week vs. less than 40 hours per week), and OR = 1.811 (working with night shift vs. without night shift). Compared with those with monthly income < 3 000 yuan, exercise frequency < 1 time per week and sleep time < 6 h per day, those with monthly income > 3 000 yuan (OR = 0.098 - 0.133), exercise frequency 1 time per week(OR = 0.308 - 0.603) and sleep time 6 h per day(OR = 0.300 - 0.334) had a lower risk of job burnout (P < 0.05). The higher the scores of social support (OR = 0.667) and return(OR = 0.605), the lower the risk of burnout of community medical personnel(P < 0.05);the higher the scores of giving (OR = 2.468)and intrinsic input (OR = 1.549), the greater the risk of burnout of community medical personnel(P < 0.05). Conclusions: During the epidemic prevention and control period, there was a certain degree of job burnout among community medical personnel. We can strengthen the intervention from individuals, organizations and society aspects and reduce the job burnout of community medical personnel by improving the level of professional skills, reasonable scheduling, appropriate exercise, and strengthening psychological counseling.

11.
Child Care in Practice ; 29(2):205-221, 2023.
Article in English | EMBASE | ID: covidwho-2266563

ABSTRACT

This study used a semi-structured approach interviewing 22 participants currently working in playwork. Participants were asked what they thought was the purpose of playwork and comment on their playwork practice because of the lockdown from COVID-19 in the United Kingdom (UK). Using thematic analysis, three purposes of playwork practice were identified: advocacy;compensatory and facilitation. In relation to their playwork, the lockdown resulted in playwork practice stopped and staff being furloughed. For others, playwork practice continued which was either non-face--to face by providing resources or there was a change of focus, for example providing online play sessions or working in a "hub" located in schools reflecting the three themes identified as the purpose of playwork. This study identified the adaptable and versatile nature of playwork that has enabled some form of playwork practice to still operate being facilitated more as a compensatory outreach provision, whether virtually or supplying or resources during the COVID-19 lockdown and the importance of maintaining relationships with the children and families in the communities where playwork provision so continuing to advocate the importance of play in children's lives. These qualities of playwork have a lot to offer once the restrictions have been lifted in both playwork-specific provision such as adventure playgrounds but also in other contexts where playwork practice is undertaken. This includes schools and could also include pre-school and daycare provision.Copyright © 2021 The Child Care in Practice Group.

12.
Journal of Substance Use ; 2023.
Article in English | EMBASE | ID: covidwho-2259541

ABSTRACT

Background: This study was designed to investigate patterns and risk factors for substance use among obstetrical patients who gave birth during the early period of the pandemic, and their partners. Method(s): Cross-sectional survey of obstetrical patients between March 17th and June 16th, 2020, at The Ottawa Hospital, Ottawa, Canada. Substance use was a composite measure of any alcohol, tobacco, or cannabis use since COVID-19 began. Four outcomes included: any participant substance use or increase in substance use, any partner substance use or increase in substance use. Adjusted risk ratios (ARR) and 95% confidence intervals (CI) are presented. Finding(s): Of 216 participants, 113 (52.3%) and 15 (6.9%) obstetrical patients reported substance use and increased use, respectively. Those born in Canada (ARR: 2.03;95% CI: 1.27-3.23) and those with lower household income (ARR: 1.38;95% CI: 1.04-1.85) had higher risk of substance use. Those with postpartum depression (ARR: 5.78;95%CI: 2.22-15.05) had the highest risk of increased substance use. Families affected by school/daycare closure reported a higher risk of increased partner substance use (ARR: 2.46;95% CI:1.38-4.39). Conclusion(s): This study found that risk factors for substance use included demographics (i.e., being born in Canada, income), mental health (postpartum depression), and school/childcare closures.Copyright © 2023 Taylor & Francis Group, LLC.

13.
European Respiratory Journal Conference: European Respiratory Society International Congress, ERS ; 60(Supplement 66), 2022.
Article in English | EMBASE | ID: covidwho-2250211

ABSTRACT

Objective: To evaluate the role of passive smoking (PS) on the incidence of wheezing and overall respiratory morbidity in infants born during the first peak of the coronavirus (COVID-19) pandemic, compared to infants born during the preceding year. Method(s): We used data collected in our recently published retrospective birth cohort study of 588 infants, 294 in each group, born in February-March 2020 (COVID-19 group) compared to a control group born in February-March 2019 (pre-COVID-19 group), at one year of age, using parental, telephone questionnaires. The primary outcome of wheezing/bronchodilator were similarly decreased, in PS and in non-PS (NPS)1. We further, conducted a post-hoc subgroup analysis of the respiratory outcomes: recurrent wheezing, emergency-room (ER) visits, pneumonia and admissions due to lower-respiratory-tract-infections (LRTI), to account for PS exposure. Atopy, daycare attendance, breastmilk, cesarean-section, siblings and gestational age were included in logistic regression models. Result(s): Demographic, perinatal, and atopic characteristics were similar between the groups. In NPS, secondary outcomes, including wheezing (OR 0.43, 95%CI 0.24-0.76), LRTI admissions (OR 0.1, 95%CI 0.01-0.89), recurrent wheezing (OR 0.28, 95%CI 0.11-0.7), ER admissions (OR 0.32, 95%CI 0.13-0.8) and pneumonia (OR 0.16, 95%CI 0.04-0.57) showed significant decreases during the COVID-19 first year pandemic. However, in PS, we did not observe these decreases in the respiratory morbidities. Conclusion(s): This study uncovers the overwhelming hazard of PS in abolishing the effect of the first year of COVID19 pandemic lock-downs, on infant's major respiratory morbidities.

14.
Research in Psychotherapy: Psychopathology, Process and Outcome ; 25(Supplement 1):33, 2022.
Article in English | EMBASE | ID: covidwho-2279175

ABSTRACT

Introduction: The Sars-Covid-19 pandemic situation has placed services dedicated to the care and rehabilitation of patients with psychotic disorders in the face of the choice of which therapeutic resources should be provided "in-person" and which "remotely". The choice of the two authors was to maintain most of the group activities "in-person", binding the participants to all the restrictions set by the norms, and to translate "remotely" mainly the individual activities. This choice was the result of a reflection of the working group, stemming from concern that a practice carried out "remotely" and "in group" in an already extremely compromised group of patients might further impair the transformative effect of the treatment itself. The underlying hypothesis was that the lack of a real physical presence and the loss of sensory input that allow one to "listen to the patient with all the senses" (Bastianini, 2019) might affect the possibility to access pre-symbolic experiences, experiences that cannot be evoked and expressed in words and that usually emerge not through verbal and symbolic communication but through nonverbal one. Method(s): In particular, this consideration has been applied from the beginning to the Photolangage © group, in which participants are already stimulated by a verbal content and asked to find answers without the use of words, through the physical choice of some photos after a "silent observation" of a selection of images taken by the conductors from some dossier;just at a subsequent, participants are encouraged to translate their choice into word, and then to share all their reflections and feelings with the rest of the group. All these steps - seen as key elements of this kind of group setting - were considered "untranslatable" as a step of a "remote" setting for this kind of groupusers, while in other contexts (e.g., didactic field) they were adopted effectively by the two authors. Thus, the hypothesis is that it was the pathology and level of functioning of the targeted treatment subjects that was mandatory for the choice rather than administration procedure of the treatment itself. Result(s): Finally, despite the limitations given by the pandemic (e.g., use of devices before and during the group session, distancing, reduction of the number of participants), group members have expressed their gratitude for the guarantee of effective treatment, experiencing a continuity in the sense of being "taken care of" and "thought about" by services. "In-person" treatment also provided the fostering and maintaining moments of "good sociability" (Corbella, 2021) among group members, who often lack it due to the consequences of their pathology and at a time when the pandemic situation affected actually that dimension.

15.
Journal of Child Nutrition and Management ; 46(2), 2022.
Article in English | GIM | ID: covidwho-2264797

ABSTRACT

PURPOSE/OBJECTIVES: The purpose of this study was to identify the ways in which the COVID-19 pandemic affected foodservice operations within urban Kansas childcare centers. METHODS: Three COVID-19-related questions were added to an online survey of Child and Adult Care Food Program (CACFP) participating childcare centers located throughout Kansas. Responses were collected from July through August, 2020. Descriptive statistics and thematic analysis of open-ended responses were used to identify common concerns. RESULTS: Seventy-nine of the 138 childcare centers invited to complete the COVID-19-related questions responded (57.2% participation rate). The majority (n=56, 70.1%) reported decreased enrollment, whereas a small number (n=9, 11.4%) reported an increase. Approximately twothirds of the centers (n=49, 62.0%) reported foodservice operation modifications owing to COVID-19-related challenges. Three overarching themes were discovered within the centers' responses: (a) procurement challenges including decreased availability and increased cost of foods, (b) changes in meal service including shifting to disposable tableware and ceasing familystyle meal service, and (c) menu and production changes in response to enrollment changes and product availability issues. APPLICATION TO CHILD NUTRITION PROFESSIONALS: Future consideration for CACFP participants include shifting to more shelf-stable foods when faced with food availability issues and utilizing more cost-effective food purchasing options, which might be attained through group purchasing organizations. Well-developed emergency plans such as emergency menus should include plans for procurement challenges. Resources and training to increase understanding and knowledge of CACFP meal pattern guidelines may make menu changes based on availability easier or less challenging. Best practice guidelines, such as family-style meals, may have to take health and safety measures into consideration. As centers continue to experience COVID-19-related issues and plan for a "return to normal", child nutrition professionals can fulfill an important role in helping centers adapt their foodservice operations to meet the challenge.

16.
Gerontol Geriatr Med ; 9: 23337214231156304, 2023.
Article in English | MEDLINE | ID: covidwho-2273707

ABSTRACT

This study described clients' experiences within adult day care (ADC) and its related impacts. A multisite case study was conducted with 26 older adults from six ADCs in Tokyo, with interviews and field observations conducted between November 2020 and July 2022. The transcribed interviews and field notes were analyzed qualitatively. Three categories pertaining to context ("guilt and resignation to the current living conditions," "desire for social connection despite frustrating limitations," and "supported life based on weekly ADC routine") and four categories about the experiences within ADC ("savoring disability- and age-friendly conversations," "feeling happy about something new and positive," "challenges for changes in self-image," and "discomfort with others and the waste of time") were extracted. Clients' increased vulnerability due to disabilities and COVID-19 affected their experiences. ADCs provide a safe place for interaction, and their use must be encouraged to develop a disability- and age-friendly society.

17.
Aging Clin Exp Res ; 35(4): 729-744, 2023 Apr.
Article in English | MEDLINE | ID: covidwho-2272988

ABSTRACT

Dementia Day Care Centres (DDCCs) are defined as services providing care and rehabilitation to people with dementia associated with behavioural and psychological symptoms (BPSD) in a semi-residential setting. According to available evidence, DDCCs may decrease BPSD, depressive symptoms and caregiver burden. The present position paper reports a consensus of Italian experts of different disciplines regarding DDCCs and includes recommendations about architectural features, requirements of personnel, psychosocial interventions, management of psychoactive drug treatment, prevention and care of geriatric syndromes, and support to family caregivers. DDCCs architectural features should follow specific criteria and address specific needs of people with dementia, supporting independence, safety, and comfort. Staffing should be adequate in size and competence and should be able to implement psychosocial interventions, especially focused on BPSD. Individualized care plan should include prevention and treatment of geriatric syndromes, a targeted vaccination plan for infectious diseases including COVID-19, and adjustment of psychotropic drug treatment, all in cooperation with the general practitioner. Informal caregivers should be involved in the focus of intervention, with the aim of reducing assistance burden and promoting the adaptation to the ever-changing relationship with the patient.


Subject(s)
COVID-19 , Dementia , Humans , Aged , Dementia/therapy , Dementia/psychology , Day Care, Medical , Syndrome , COVID-19/prevention & control , Caregivers/psychology
18.
Microbiol Spectr ; 11(1): e0417422, 2023 02 14.
Article in English | MEDLINE | ID: covidwho-2240744

ABSTRACT

The aim of this study was to provide information about immunity against COVID-19 along with risk factors and behavior among employees in day care facilities and preschools (DCS) in Denmark. In collaboration with the Danish Union of Pedagogues, during February and March 2021, 47,810 members were offered a point-of-care rapid SARS-CoV-2 antibody test (POCT) at work and were invited to fill in an electronic questionnaire covering COVID-19 exposure. Seroprevalence data from Danish blood donors (total Ig enzyme-linked immunosorbent assay [ELISA]) were used as a proxy for the Danish population. A total of 21,018 (45%) DCS employees completed the questionnaire and reported their POCT result {median age, 44.3 years (interquartile range [IQR], [32.7 to 53.6]); females, 84.1%}, of which 20,267 (96.4%) were unvaccinated and included in analysis. A total of 1,857 (9.2%) participants tested seropositive, significantly higher than a seroprevalence at 7.6% (risk ratio [RR], 1.2; 95% confidence interval [CI], 1.14 to 1.27) among 40,541 healthy blood donors (median age, 42 years [IQR, 28 to 53]; males, 51.3%). Exposure at work (RR, 2.9; 95% CI, 2.3 to 3.6) was less of a risk factor than exposure within the household (RR, 12.7; 95% CI, 10.2 to 15.8). Less than 25% of participants reported wearing face protection at work. Most of the participants expressed some degree of fear of contracting COVID-19 both at work and outside work. SARS-CoV-2 seroprevalence was slightly higher in DCS staff than in blood donors, but possible exposure at home was associated with a higher risk than at work. DCS staff expressed fear of contracting COVID-19, though there was limited use of face protection at work. IMPORTANCE Identifying at-risk groups and evaluating preventive interventions in at-risk groups is imperative for the ongoing pandemic as well as for the control of future epidemics. Although DCS staff have a much higher risk of being infected within their own household than at their workplace, most are fearful of being infected with COVID-19 or bringing COVID-19 to work. This represents an interesting dilemma and an important issue which should be addressed by public health authorities for risk communication and pandemic planning. This study design can be used in a strategy for ongoing surveillance of COVID-19 immunity or other infections in the population. The findings of this study can be used to assess the need for future preventive interventions in DCS, such as the use of personal protective equipment.


Subject(s)
Antibodies, Viral , COVID-19 , Child Day Care Centers , Faculty , Schools , Adult , Female , Humans , Male , COVID-19/epidemiology , Cross-Sectional Studies , Denmark/epidemiology , Risk Factors , SARS-CoV-2 , Seroepidemiologic Studies
19.
Value in Health ; 25(12 Supplement):S293, 2022.
Article in English | EMBASE | ID: covidwho-2211001

ABSTRACT

Objectives: Hospitalization At Home (HAH), facility delivering hospital care at home, constitutes an alternative to hospitalization for ICI infusion. This work aims to describe the evolution of ICI administration in HAH between 2019-2020 in the COVID epidemic context, to characterize patients and their care pathways. Method(s): Through national hospital database (PMSI), all patients with at least one ICI infusion per year, 2019 and 2020 (including Covid-19 lock-down), were identified with a 6-year retrospective chain of all ICI infusion stays. Patients' journey was analyzed (days number before and during HAH period, alternation HAH/ day care unit (DCU) infusion), based on descriptive analysis and treatment sequences clustering algorithms (TAK). Result(s): HAH patients significantly increased from 60 in 2019 to 339 in 2020 but remained limited (0,67% of 2020 ICI patients). Infusions have significantly increased during Covid-19 lock-down periods and remain at a higher level during the rest of 2020. Mean age and gender characteristics tend to be similar (62 and 66 years old, 37% and 33% women). Lung cancer (77% and 64%) and melanoma (23% and 27%) remained the most frequent tumors treated, but head and neck cancers (8%) and renal carcinoma (3%) were newly observed in 2020. Most administered ICIs in 2020 remained nivolumab (49%) and pembrolizumab (41%). In 2020, number of days before HAH was still close to a year (340days) and higher than the days number spent in HAH (n=110). In 2019 and 2020, treatment sequence analysis shows lung cancer patients mainly managed in HAH after first HAH infusion as well as for melanoma in 2019. In 2020, it shows different patterns for melanoma with HAH/DCU alternation dominance after first HAH infusion. Conclusion(s): Despite easier HAH access since Covid-19, HAH remains limited. French Society for Cancer Immunotherapy 2020 recommendations should contribute to HAH development. Copyright © 2022

20.
British Journal of Oral and Maxillofacial Surgery ; 60(10):e69, 2022.
Article in English | EMBASE | ID: covidwho-2209894

ABSTRACT

Introduction/Aims: Historically orthognathic patients have required overnight admission owing to airway risk, risk of bleeding, pain, nausea and vomiting. (1) More recently patient drivers, NHS pressures, improved anaesthesia and operator efficiency (2) have led us to look for ways to deliver the service on a daycare protocol.(3) Material(s) and Method(s): We proposed a single surgeon pilot study in line with governance and safety standards. Peri operative criteria were defined as ASA1/2, support at home, standardised pre, intra and post operative medication and a set anaesthetic technique. Surgical parameters were set as a Le Fort 1 or BSSO osteotomy with intra operative wafers and post operative orthodontic review available. A prospective study from August 2017 to August 2021 was carried out. Results/Statistics: 35 patients met the criteria, 15 were treated on the day case protocol. 4 patients were excluded for surgical complications and 3 reported they would not have coped at home. 8 were successfully managed on the pathway. Barriers to the study included covid-19 restrictions, mixed elective and emergency operating, delays to theatre and patient acceptance varied. Conclusions/Clinical Relevance: Single jaw day case orthognathic surgery may increase productivity and reduce cancellations on the day. A successful pathway depends on good nursing, anaesthetic and orthodontic support. We report our experience of a pilot pathway and present our written protocols for each discipline. Managing patient selection and expectations is critical. Copyright © 2022

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